's-Hertogenbosch Oost railway station serves the city of 's-Hertogenbosch in the North Brabant province of the Netherlands.

The station was opened in 1987 and is located on the Brabantselijn (Nijmegen - Tilburg). The train services are operated by Nederlandse Spoorwegen.

The main station of 's-Hertogenbosch is 's-Hertogenbosch.

The following services currently call at 's-Hertogenbosch Oost:

• 2x per hour local services (stoptrein) Nijmegen - Oss - 's-Hertogenbosch

• NS website (in Dutch)
• Dutch Public Transport journey planner (in Dutch)