The Órbigo River is a river in the provinces of León and Zamora, Spain. It begins at the convergence of the Luna River and the Omaña River in the village of Secarejo, in the Cimanes del Tejar municipality. Decades ago, that confluence was some km. before, in the town of Santiago del Molinillo. It flows from north to south through the province of León and ultimately flows into the Esla River below Benavente.

How the river came to have this name is not known. According to the linguist E. Bascuas, the toponym Órbigo, would come from a Paleo-European hydronymic theme *urw-, derived from the Indo-European root *er- 'flow, move', with a hydronymic meaning. The first mention is from Hydatius "Ad fluvium nomine Urbicum". The name could also have Basque roots, from the words "Ur" (water) and "Bi" (two). There exists a theory that the river now called the Luna should be the real start of the Órbigo. Although it was the same river, in the times of the Conde Luna, it was ordered to change that name of the river so that the part in the county would have its name.

• Duerna
• Tuerto
• Jamuz
• Eria
• Special tributary: Presa Cerrajera, which splits from the Órbigo and later flows into it again

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  In 1433 on this spot—the bridge over the river Órbigo—Suero de Quiñones and ten of his knights challenged all comers to a Pas d'Armes, promising to "break 300 lances" before moving on.
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  Medieval bridge over the Órbigo River in Hospital de Órbigo, León.
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  Órbigo river watershed.
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  Another view of the union of the Luna and Omaña rivers, forming the Órbigo.

• List of rivers of Spain

41°59′23.62″N 5°42′23.58″W / 41.9898944°N 5.7065500°W / 41.9898944; -5.7065500