Łopuchowo [wɔpuˈxɔvɔ], is a village in the administrative district of Gmina Krasnopol, within Sejny County, Podlaskie Voivodeship, in north-eastern Poland. It lies approximately 7 kilometres (4 mi) east of Krasnopol, 5 km (3 mi) south-west of Sejny, and 110 km (68 mi) north of the regional capital Białystok.