Śwignajno Wielkie [ɕfiɡˈnai̯nɔ ˈvjɛlkʲɛ] (German: Groß Schwignainen) is a settlement in the administrative district of Gmina Ruciane-Nida, within Pisz County, Warmian-Masurian Voivodeship, in northern Poland. It lies approximately 5 kilometres (3 mi) north of Ruciane-Nida, 20 km (12 mi) north-west of Pisz, and 69 km (43 mi) east of the regional capital Olsztyn.

The settlement has a population of 30.