Žygimantų Street is a street in the Vilnius Old Town, Vilnius, Lithuania. It follows the left bank of the Neris River on the stretch between the Mindaugas Bridge separating it from the Arsenal street and the Green Bridge separating it from the Albertas Goštautas street.

Before World War II, while in the interbellum Poland the street was named ulica Zygmuntowska (Sigismunds' Street) after the kings of Poland and Grand Dukes of Lithuania, Sigismund I the Old, Sigismund II Augustus, and Sigismund III Vasa. During the Soviet times it was part of the street named after Karolis Požela.

• Žygimantų 1: Wroblewski Library of the Lithuanian Academy of Sciences
• Žygimantų 2: Supreme Administrative Court of Lithuania
• Žygimantų 6: Lithuanian Children's Foundation [lt]
• Žygimantų 10: Stasys Šalkauskis's house