The A2 Autoroute is a French autoroute that travels 76 km (47 mi) from the A1 near the commune of Combles in Picardy to the border with Belgium, where it continues on as the Belgian motorway A7. The entire length is concurrently designated as European route E19.

In conjunction with the A1 autoroute and the Belgian A7 it is the main route between Paris and Brussels. Until other more direct motorway routes are completed it is also the fastest route from Paris to the Belgian city of Liège.

From Combles to Cambrai, the autoroute is managed by the Société des Autoroutes du Nord et de l'Est de la France (SANEF) and is a toll road, with no exits on the southernmost 22.8 kilometres (14.2 mi) of the A2 between the A1 and the A26 at Graincourt-lès-Havrincourt. From Cambrai onward it is a non-toll autoroute managed by the government of the Nord department. Two lanes travel in each direction.

The A2 was opened in two stages in 1972. The first stage from junction 15 to the Belgian border opened on 28 March. The remainder, from Junction 15 to the interchange with the A1 opened on 19 December 1972.

This article contains a bulleted list or table of intersections which should be presented in a properly formatted junction table. Please consult this guideline for information on how to create one. Please improve this article if you can. (December 2021)

Exit/Junction	Destination
	A 1
	A 26 – Calais, Reims
14	Cambrai
15	Bouchain
16	Hordain
17	Douchy-les-Mines
	A 21 – Douai
18	Denain
19  Northbound only	Parc d'activités de l'aerodrome
20	Valenciennes - le Vignoble, ZI Prouvy-Rouvignies
	A 23 – Lille, Saint-Amand-les-Eaux
21	Valenciennes - Centre
21a	Aulnoy-lez-Valenciennes
21b	Valenciennes - Centre
22a  Northbound only	D 649 – Maubeuge
22b  Northbound only	Valenciennes - le Roleur
23	D 659 – St. Saulve,, Maubeuge
23.1	Sebourg, Parc D'Activites de la Vallee de l'Escaut
24	Onnaing
25	Quievrechain, Bruay-sur-l'Escaut
26  (Northbound exit, Southbound entrance)	Crespin
Belgian Border; A 2 becomes Belgian road A7

European Route	Location
E19	entire length