The A4260 is a road that leads from the A422 Henneff Way, Banbury, to Frieze Way near Oxford, England.

The route followed by the road is that of a prehistoric ridgeway between the valleys of the rivers Cherwell and Evenlode. The Romans adopted the route and paved it from north of Oxford to Akeman Street at Sturdy's Castle.

The route remained in use through the medieval period, as described by John Ogilby in 1675, as the primary way between Oxford and Banbury. In the 18th century, the route was turnpiked.

Until 1990, the road was part of the A423 and the major route from Banbury to Oxford. It was renumbered to encourage the traffic that formerly used this route to use the M40.

• Highlighted Route of the A4260 on Google Maps

51°57′08″N 1°19′07″W / 51.9523°N 1.3186°W / 51.9523; -1.3186 (A4260 road)