The Anna L. Nickel telescope is a 1-meter reflecting telescope located at Lick Observatory in the U.S. state of California.

The smaller dome on the main building at Lick had originally held the secondhand 12-inch Clark refracting telescope, the first telescope to be used at Lick. In 1979 it was replaced with the Anna L. Nickel telescope, a 1-meter reflecting telescope. The telescope is named for Anna L. Nickel, a San Francisco native who donated $50,000, a large portion of her estate, to the Observatory.

The Nickel telescope was built entirely by UC Santa Cruz personnel and utilized many spare parts, including a replacement mirror for the Crossley Reflector. It eased demand for time on the 120-inch C. Donald Shane telescope by taking on research programs that do not require the Shane's greater light-gathering power. Due to its optical design, it can use the same instruments as the Shane so instruments can be tested on it.

• List of largest optical telescopes in the 20th century
• List of astronomical observatories