The Roman Catholic Diocese of Isangi (Latin: Isangien(sis)) is a Latin suffragan diocese in the ecclesiastical province of Kisangani in the Democratic Republic of the Congo .

Its cathedral episcopal see is the Cathédrale Marie Médiatrice (Mary Mediatrix) located in the city of Isangi .

• 14 June 1951: Established as Apostolic Prefecture of Isangi on territories split off from the then Apostolic Vicariate of Basankusu, Apostolic Vicariate of Coquilhatville, Apostolic Vicariate of Lisala and Apostolic Vicariate of Stanleyville
• 2 July 1962: Promoted as Diocese of Isangi

• Bishops of Isangi (Latin Rite), below
  • Bishop Dieudonné Madrapile Tanzi (2 April 2016 – Present)
  • Bishop Camille Lembi Zaneli (2 June 2000 – 8 July 2011)
  • Bishop Louis Mbwôl-Mpasi, O.M.I. (1 September 1988 – 20 May 1997), appointed Bishop of Idiofa
  • Bishop Lodewijk Antoon Jansen, S.M.M. (2 July 1962 – 20 April 1988); see below
• Prefect Apostolic of Isangi (Latin Rite), below
  • Father Lodewijk Antoon Jansen, S.M.M. (10 January 1952 – 2 July 1962); see above

• Louis Mbwôl-Mpasi, O.M.I. (1984-1988), appointed Bishop here

• Roman Catholicism in the Democratic Republic of the Congo

• GCatholic.org
• Catholic Hierarchy

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