Büsum-Wesselburen is an Amt ("collective municipality") in the district of Dithmarschen, in Schleswig-Holstein, Germany. Its seat is in Büsum. It was formed on 25 May 2008 from the former Ämter Kirchspielslandgemeinde Büsum, Kirchspielslandgemeinde Wesselburen and the town Wesselburen.

The Amt Büsum-Wesselburen consists of the following municipalities (with population in 2005):

Büsum (4,880) Büsumer Deichhausen (345) Friedrichsgabekoog (71) Hedwigenkoog (271) Hellschen-Heringsand-Unterschaar (169) Hillgroven (86) Norddeich (430) Oesterdeichstrich (273) Oesterwurth (274)

Reinsbüttel (427) Schülp (489) Strübbel (96) Süderdeich (536) Warwerort (284) Wesselburen (3,112) Wesselburener Deichhausen (142) Wesselburenerkoog (151) Westerdeichstrich (908)

54°13′00″N 8°55′00″E / 54.2167°N 8.9167°E / 54.2167; 8.9167