Barnes Meadow is a 29.4 hectare Local Nature Reserve in Northampton. An area of 20 hectares is managed by the Wildlife Trust for Bedfordshire, Cambridgeshire and Northamptonshire.

The site includes a stretch of the River Nene, meadows and a redundant arm of the river. There are many dragonflies including brown hawkers, and a large population of grass snakes. Birds include grey herons, kingfishers and great crested grebes.

There is access from the Nene Way footpath, which passes through the site.