Blackthorn railway station was a railway station serving the village of Blackthorn, Oxfordshire, England. It was on what is now known as the Chiltern Main Line.

Blackthorn was one of six new stations that the Great Western Railway provided when it opened the high-speed Bicester cut-off line between Princes Risborough and Kings Sutton in 1910. The line became part of the Western Region of British Railways on nationalisation in 1948. British Railways closed Blackthorn station in 1953.

Preceding station	Historical railways			Following station
Bicester North Line and station open		Great Western Railway Bicester "cut-off"		Brill & Ludgershall Line open, station closed

• Butt, R. V. J. (October 1995). The Directory of Railway Stations: details every public and private passenger station, halt, platform and stopping place, past and present (1st ed.). Sparkford: Patrick Stephens Ltd. ISBN 978-1-85260-508-7. OCLC 60251199. OL 11956311M.
• Jowett, Alan (2000). Jowett's Nationalised Railway Atlas (1st ed.). Penryn, Cornwall: Atlantic Transport Publishers. ISBN 978-0-906899-99-1. OCLC 228266687.

51°52′40″N 1°05′40″W / 51.87782°N 1.09447°W / 51.87782; -1.09447