At 9:00 pm, USN, USAF, and Royal Navy (RN) forces launched several salvos totaling fifty Tomahawkcruise missiles against Taliban military and communications facilities and suspected terrorist training camps. The timing was chosen to coincide with the arrival of the strike aircraft, which dropped a variety of bombs including Mk 82s, JDAMs, AGM-84s, AGM-154s and laser-guided bombs. According to in-country sources reporting to CNN, targets within Kandahar included Taliban strongholds, as well as the houses of Arab foreigners who worked with the Taliban regime. One of the primary targets for the airstrike in Kandahar was Mullah Omar. The attacking aircraft were met with sporadic fire from Taliban anti-aircraft artillery batteries and surface-to-air missiles. The U.S. considered the attacks, conducted against the cities of Kabul, Jalalabad and Herat, to be successful as the goal of neutralizing the Taliban's air defense was met.
To court and provide relief for the Afghan people, food and supplies were dropped into the region. Two C-17transports delivered 37,500 daily rations by airdrop to refugees inside Afghanistan on the first day of the attack. Relief efforts faced setback, however, from Taliban interference. World Food Programme storehouses in Kandahar were raided and surrendered to Taliban soldiers, who "seized about 7,000 tons of food." Hoping to avoid a backlash by civilians, the USAF deployed an EC-130E propeller aircraft to broadcast a message that the Taliban and its allies were the only targets of the attacks, not civilians.
Following the successful airstrikes against the city, and after rapid setbacks experienced by Taliban forces across the country, much of the military might held directly and indirectly by Mullah Omar was consolidated in the city of Kandahar. On November 18, the United States enlisted the help of Gul Agha Sherzai, an anti-Taliban commander and previous Governor of Kandahar Province. On November 25, the U.S. airlifted a contingent of 750 Marines from the 15th Marine Expeditionary Unit to create a forward base at Camp Rhino, located 100 miles (160 km) south of Kandahar. At this time, the allied commanders were also finalizing the decision to send British paratroopers from the 2nd Battalion, The Parachute Regiment. These events set the stage for the taking of Kandahar and Taliban surrender on December 7.