Brezzo di Bedero is a comune (municipality) in the Province of Varese in the Italian region Lombardy, located about 70 kilometres (43 mi) northwest of Milan and about 20 kilometres (12 mi) northwest of Varese.

Brezzo di Bedero borders the following municipalities: Brissago-Valtravaglia, Cannero Riviera, Germignaga, Oggebbio, Porto Valtravaglia.