Brindisi railway station (IATA: BQD) (Italian: Stazione di Brindisi) is the main station serving the city and comune of Brindisi, in the region of Apulia, southern Italy. Opened in 1865, it forms part of the Adriatic Railway (Ancona–Lecce), and is also a junction for, and terminus of, the Taranto–Brindisi railway.

The station is currently managed by Rete Ferroviaria Italiana (RFI). However, the commercial area of the passenger building is managed by Centostazioni. Train services are operated on behalf of Trenitalia. Each of these companies is a subsidiary of Ferrovie dello Stato (FS), Italy's state-owned rail company.

Brindisi railway station is situated at Piazza Francesco Crispi, at the southwest edge of the city centre.

The station was opened on 29 April 1865, during an era of economic expansion, upon the inauguration of the Bari–Brindisi section of the Adriatic Railway. Nearly nine months later, on 15 January 1866, the Adriatic Railway was extended from Brindisi to Lecce.

Built like a typical transit station, the passenger building had a structure characterized by a sloping flat roof covering the two through tracks and the pedestrian level crossing between platforms.

On 30 December 1886, Brindisi became a junction station, when the final section of the Taranto–Brindisi railway was opened, between Mesagne and Brindisi.

Today, the station has eight tracks used by Trenitalia, and a link with the Brindisi Marittima railway station, once connected by ship to Greece, but now dismantled.

The station was included in the Centostazioni program of rehabilitation of the main Italian stations. At Brindisi, the rehabilitation project includes an increase and reorganization of space for passengers with significant improvements in services.

The trains stopping at the station range from regional services to InterCity and Eurostar trains. The following list shows the services calling here, and the main stations. Eurostar and Intercity are express services, Treno Regionale are services that stop at all/most stations.

The station is served by the following services:

• High speed services (Frecciargento) Rome - Foggia - Bari - Brindisi - Lecce
• High speed services (Frecciabianca) Milan - Parma - Bologna - Ancona - Pescara - Foggia - Bari - Brindisi - Lecce
• High speed services (Frecciabianca) Turin - Parma - Bologna - Ancona - Pescara - Foggia - Bari - Brindisi - Lecce
• High speed services (Frecciabianca) Venice - Padua - Bologna - Ancona - Pescara - Foggia - Bari - Brindisi - Lecce
• Intercity services Bologna - Rimini - Ancona - Pescara - Foggia - Bari - Brindisi - Lecce
• Night train (Intercity Notte) Rome - Foggia - Bari - Brindisi - Lecce
• Night train (Intercity Notte) Milan - Parma - Bologna - Ancona - Pescara - Foggia - Bari - Brindisi - Lecce
• Night train (Intercity Notte) Milan - Ancona - Pescara - Foggia - Bari - Taranto - Brindisi - Lecce
• Night train (Intercity Notte) Turin - Alessandria - Bologna - Ancona - Pescara - Foggia - Bari - Brindisi - Lecce
• Regional services (Treno regionale) Bari - Monopoli - Brindisi - Lecce
• Local services (Treno regionale) Taranto - Francavilla Fontana - Brindisi

Preceding station		Trenitalia		Following station
Bari Centrale toward Roma Termini		Frecciargento		Lecce Terminus
Bari Centrale toward		Frecciabianca		Lecce toward
Bari Centrale toward		Frecciabianca		Lecce toward
Bari Centrale toward		Frecciabianca		Lecce toward
Ostuni toward Bologna Centrale		InterCity		Lecce Terminus
Ostuni toward Milano Centrale		InterCity		Lecce Terminus
Ostuni toward Roma Termini		Intercity Notte		Lecce Terminus
Ostuni toward Milano Centrale		Intercity Notte		Lecce Terminus
Francavilla Fontana toward Milano Centrale		Intercity Notte		Lecce Terminus
Ostuni toward Torino Porta Nuova		Intercity Notte		Lecce Terminus
San Vito dei Normanni toward Bari Centrale		Treno regionale		San Pietro Vernotico toward Lecce
Carovigno toward Foggia		Treno regionale		San Pietro Vernotico toward Lecce
Mesagne toward Taranto		Treno regionale		Terminus

• Brindisi Marittima railway station
• History of rail transport in Italy
• List of railway stations in Apulia
• Rail transport in Italy
• Railway stations in Italy

Media related to Brindisi railway station at Wikimedia Commons