Brno-Chrlice is a city district in the south part of the city of Brno, Czech Republic. It consists of the municipal part and cadastral territory of Chrlice (German: Chirlitz), originally an independent municipality that was annexed to Brno in 1971. It has an area of 9.49 km. The current city district was established on November 24, 1990. About 3,600 people live here.

Since 2005, Brno-Chrlice also has its own flag. For the purposes of the senate elections, Brno-Chrlice is included in electoral district 58 of Brno-City District.

The local name Chrlici was derived from the personal name Chrla (the basis of which is either the verb chrliti - "to throw" or the adjective chrlý - "quick") and meant "Chrla's people". The German name (Kirlitz in the oldest documents) originated from Czech.

The oldest written mention of Chrlice dates from 1320. They were already in the possession of the Archdiocese of Olomouc at that time, but the village was divided into fiefs, the holders of which changed during the following centuries. At the end of the 16th century, Chrlice became the center of the episcopal estate. In 1787, the village of Růžový, which was an independent municipality between 1875 and 1949, was founded on the site of a parceled yard, in close proximity to Chrlice.

Chrlice (and Růžová) were then annexed into Brno on November 26, 1971. Until December 31, 1975, they were an independent district of Brno with their own local national committee. The district was first called Brno XIV-Chrlice, from May 1, 1972, only Brno-Chrlice. From January 1, 1976, to November 23, 1990, Chrlice was part of the Brno IV district. Since November 23, 1990, the current city district of Brno-Chrlice was established.

Chrlice essentially has the character of a large village, which is, however, disturbed by a smaller housing estate and, especially from the south and west, by the high-rise facilities of the local industrial area. Outside the Chrlice urban area, there are extensive areas of arable land, which fill most of Chrlice. Chrlice belongs to the T2 region - the driest and warmest region of the Czech Republic.

Brno-Chrlice borders on the north with Brno-Tuřany (Holásky and Tuřany), the municipalities of Modřice in the west, Rebešovice and Otmarov in the south, Sokolnice in the east.

The cadastral territory of Chrlice is further divided into 4 basic settlement units.

Basic settlement unit	Population (2011)	Population (2021)	Change
Chrlice	3,662	3,490	-4.7%
Splaviska	0	0	+0%
U přerovské trati	0	3	-
Roviny	60	120	+100.0%

Historical population

Year Pop. ±% 1869 1,135 —     1880 1,328 +17.0% 1890 1,534 +15.5% 1900 1,608 +4.8% 1910 1,694 +5.3%	Year Pop. ±% 1921 1,814 +7.1% 1930 2,314 +27.6% 1950 2,382 +2.9% 1961 2,647 +11.1% 1970 2,565 −3.1%	Year Pop. ±% 1980 3,121 +21.7% 1991 3,110 −0.4% 2001 3,176 +2.1% 2011 3,722 +17.2% 2021 3,613 −2.9%
Source: Censuses

The fastest way to get to Chrlice is by train line S2 or R12, station Brno-Chrlice on the line 300 from Přerov to Brno.

There is bus transport on route No. 64 on the route Chrlice to Maloměřice (Červený písek). There is also line number 78 from Židenice railway station or from the Olympia shopping mall in Modřice. Next, night line number N95 from Kamenný vrch via the main railway station to the Chrlice loop. The regular bus line number 509 arrives in Chrlice from the direction of Měnín (some routes only go from/to Rajhradice).

The D2 highway passes through the western part of Chrlice.