The Brooklyn Hotel is a historic building located in Brooklyn, Iowa, United States. John Byers, who operated a grocery store and billiard hall, built the structure as a house in 1875. Subsequent owners operated a hotel here. It was known as the Brooklyn Hotel as early as 1894. Dr. Charles Busby was the exception. He operated a small hospital here in the early in the 20th century. The 2½-story building features a three-story entrance tower, bracketed eaves, window sills of limestone quarried nearby, and an irregular plan. The hotel was listed on the National Register of Historic Places in 1979.