Brudzeń Duży [ˈbrud͡zɛɲ ˈduʐɨ] is a village in Płock County, Masovian Voivodeship, in east-central Poland. It is the seat of the gmina (administrative district) called Gmina Brudzeń Duży. It lies approximately 19 kilometres (12 mi) north-west of Płock and 114 km (71 mi) north-west of Warsaw.

The village is the birthplace of scholar Pawel Wlodkowic (ca. 1370–1435).

• Brudzeń Landscape Park