Cabezamesada is a municipality located in the province of Toledo, Castile-La Mancha, Spain. According to the 2006 census (INE), the municipality has a population of 469 inhabitants.

Demographics

Historical population

Year	Pop.	±%
1900	969	—
1910	1,039	+7.2%
1920	1,119	+7.7%
1930	1,261	+12.7%
1940	1,405	+11.4%
1950	1,532	+9.0%
1960	1,342	−12.4%
1970	966	−28.0%
1981	704	−27.1%
1991	581	−17.5%
2001	494	−15.0%
2011	546	+10.5%
2021	330	−39.6%
2023	356	+7.9%
Source: ISTAT