The canton of Orange-Ouest is a French former administrative division in the department of Vaucluse and region Provence-Alpes-Côte d'Azur. It had 24,579 inhabitants (2012). It was disbanded following the French canton reorganisation which came into effect in March 2015.

The communes in the canton of Orange-Ouest:

• Caderousse
• Châteauneuf-du-Pape
• Orange (partly)
• Piolenc

44°07′10″N 4°47′25″E / 44.11944°N 4.79028°E / 44.11944; 4.79028