Castelfranco Piandiscò is a commune in the province of Arezzo, Tuscany, central Italy. It was created on 1 January 2014 from the merger of previous comuni of Castelfranco di Sopra and Pian di Scò.

It is located about 30 kilometres (19 mi) southeast of Florence and about 30 kilometres (19 mi) northwest of Arezzo.