Castiglione Chiavarese (Ligurian: O Castiggion [u kastiˈdʒuŋ]) is a comune (municipality) in the Metropolitan City of Genoa in the Italian region Liguria, located about 50 kilometres (31 mi) southeast of Genoa.

Castiglione Chiavarese borders the following municipalities: Carro, Casarza Ligure, Deiva Marina, Maissana, Moneglia.

In ancient times the area of Castiglione probably marked the border between the Ligurian and the Etruscan cultures. the modern frazione of Velva was a Roman municipium during Trajan's reign.

The Val Petronio was colonized by Benedictine monks after the fall of the Western Roman Empire; later it became a possession of the Fieschi family who, in 1276, sold Castiglione to the Republic of Genoa. In 1747, the latter built here a series of fortifications against the Austrians. In 1815, after a short Napoleonic rule, it was acquired by the Kingdom of Sardinia-Piedmont, becoming part of the newly unified Kingdom of Italy in 1861.

• Church of Sant'Antonino martire (1143)
• Conio Abbey (1664)
• Roman bridges and roads

Castiglione Chiavarese is located across the SS523 State Road connecting it to Sestri Levante, which also houses the nearest railway station.

• Figone, Fausto (1995). La Podesteria di Castiglione. Lineamenti storici. Chiavari.{{cite book}}: CS1 maint: location missing publisher (link)