Castletownbere Lifeboat Station is the base for a Royal National Lifeboat Institution (RNLI) inshore lifeboat at Castletownbere in County Cork on the south west corner of Ireland.

The west coast of Ireland faces the Atlantic Ocean but had sparse coverage from lifeboats until late in the twentieth century. In 1990 there were only four stations but by 2000 seven more had been opened. A lifeboat was sent to Castletownbere in 1997 to evaluate it as a suitable harbour and it was confirmed as a permanent station in October 1998. Poorly-located temporary crew facilities were in use for many years but a new building and moorings were brought into use on 19 May 2013 which significantly reduced the time taken for the lifeboat to put to sea.

The lifeboat was launched on 10 October 2018 to aid the Clodagh O, a trawler which had broken down and was being blown onto rocks in a Force 9 storm. The lifeboat crew managed to get a line onto the trawler and towed it back to the harbour, saving its crew of six people. The rescue was led by coxswain Dean Hegarty who was awarded an RNLI bronze medal, the first Irishman to be recognised in this way in over 10 years.

The RNLI aims to reach any vessel in distress up to 50 nmi (93 km) from the coast within 2 hours of launching. The Severn-class lifeboat at Castletownbere has a range of 250 nmi (460 km) and top speed of 25 kn (46 km/h). Adjacent lifeboats are stationed at Valentia to the north and Baltimore to the east.

On station	ON	Op. No.	Name	Class	Built	Comments
1998–2004	1118	52-36	Roy and Barbara Harding	Arun	1987	First stationed at Aran Islands. Sold in 2004 for further use as a lifeboat in Iceland.
2004	1144	52-42	Murray Lornie	Arun	1988	First stationed at Lochinver. Sold in 2005 for further use as a lifeboat in Iceland until 2023 when it was sold again for use as a workboat in Greenland.
2004–	1277	17-44	Annette Hutton	Severn	2004

• List of RNLI stations
• Royal National Lifeboat Institution lifeboats

• RNLI: Castletownbere Lifeboat Station