The Cauayan City National High School - Main is a public educational institution established in Cauayan, Isabela, Philippines. It was founded on June 3, 1997, as an extension of Cauayan Polytechnic College, now Isabela State University-Cauayan Campus.

It was formerly named Cauayan National High School since its inception and was later renamed to its present name when Cauayan, Isabela became a city on March 30, 2001. In 2013, Cauayan City National High School won as the greenest school in the Philippines.

Administration

The school is now administered by the DepEd Schools Division of Cauayan. Ms./Mrs. Maribeth Dela Peña, Secondary School Principal II serves as the newly assigned secondary school principal of Cauayan City National High School.

Education programs

Cauayan City National High School has educational programs for students for the following curriculum:

• Science, Technology, and Engineering Curriculum (STE)
• Special Program in Arts (SPA)
• Special Program in Sports (SPS)
• Special Program in Journalism (SPJ)
• Special Program in Foreign Language (SPFL)
• Basic Education Curriculum (BEC)
• Science, Technology, Engineering and Math (STEM)

The school is currently implementing Grades 7 to 10 in accordance with the K to 12 program of the Department of Education.