Centenary is an unincorporated community in Marion County, South Carolina, United States. Located along SC 41 Alt, 10.5 miles (16.9 km) south of Marion. Along the CSX Seaboard Air Line, the area is a predominantly farming community.

The community took its name from the local Centenary Methodist Church, which itself was named in commemoration of a centenary milestone in Methodism.

It was first listed as a CDP prior to the 2020 census with a population of 191.

Historical population

Census	Pop.	Note	%±
2020	191		—
U.S. Decennial Census 2020

Centenary CDP, South Carolina – Racial and Ethnic Composition
(NH = Non-Hispanic)
Note: the US Census treats Hispanic/Latino as an ethnic category. This table excludes Latinos from the racial categories and assigns them to a separate category. Hispanics/Latinos may be of any race.

Race / Ethnicity	Pop 2020	% 2020
White alone (NH)	47	24.61%
Black or African American alone (NH)	140	73.30%
Native American or Alaska Native alone (NH)	1	0.52%
Asian alone (NH)	0	0.00%
Pacific Islander alone (NH)	0	0.00%
Some Other Race alone (NH)	0	0.00%
Mixed Race/Multi-Racial (NH)	1	0.52%
Hispanic or Latino (any race)	2	1.05%
Total	191	100.00%