Chamzey Rural District (Persian: دهستان چمزئ) is in the Central District of Malekshahi County, Ilam province, Iran.

At the National Census of 2006, its population (as a part of the former Malekshahi District of Mehran County) was 3,152 in 614 households. There were 2,957 inhabitants in 733 households at the following census of 2011, by which time the district had been separated from the county in the establishment of Malekshahi County. At the most recent census of 2016, the population of the rural district was 2,722 in 774 households. The most populous of its 14 villages was Gonbad-e Pir Mohammad, with 1,573 people.