The Chesterfield House is an Antebellum house at 9625 Old Rutledge Pike in the Mascot community of northeastern Knox County, Tennessee. Built in 1838 by George W. Arnold, a physician from Roanoke, Virginia, the house is now listed on the National Register of Historic Places. It was located along a stagecoach route (roughly what is now US 11) that began in Washington, D.C., passed through Knoxville, and continued further south. Stagecoaches made stops at Chesterfield.

The mansion is a two-story brick structure with a one-story covered front porch. The porch has a balcony above, accessed off a second floor room. Architecturally, the house has Georgian influences. It remains a private residence, and is not open to the public.

• Knoxville: Fifty Landmarks. (Knoxville: The Knoxville Heritage Committee of the Junior League of Knoxville, 1976), page 24.

• National Register of Historic Places
• Knox County Historic Preservation