China Eastern Airlines Flight 583 was a commercial passenger flight from Shanghai, China, to Los Angeles, United States, operated by China Eastern Airlines. On April 6, 1993, the McDonnell Douglas MD-11 operating the flight experienced an in-flight upset due to a flight crew member inadvertently deploying the slats of the aircraft while the plane was cruising near the Aleutian Islands. The accident resulted in the death of two passengers and 156 injuries.

The aircraft involved was a McDonnell Douglas MD-11, with manufacturer serial number 48495 and registered as B-2171. It was built by McDonnell Douglas in 1991 and was equipped with three Pratt & Whitney PW4460 engines. The aircraft had logged approximately 4,810 airframe hours and 1,571 takeoff and landing cycles

12 flight attendants were onboard, including lead flight attendant Li Na Li, along with 4 cockpit crew members and 4 relief cockpit crew members.

On April 6, 1993, the McDonnell-Douglas MD-11 operating the service was making a slow left turn while cruising above the Pacific Ocean at 296 knots when about 20 minutes after the relief crew took over, one of the relief crew members, likely the captain, while attempting to fix a speed indicator issue, accidentally deployed the slats near the Aleutian Islands. While attempting to correct the pitch up caused by the slat deployment, the crew caused the plane to enter severe oscillations after repeatedly over-correcting. After losing about 5,000 ft of altitude, the aircraft stabilized and eventually made an emergency landing at Shemya Air Force Base in Shemya, Semichi Islands, Alaska.

Of the 255 passengers and crew, 60 were hospitalized, of which, 2 died. Of the cockpit crew, five received no injuries and three received serious injuries. Of the flight attendants, eight received no injuries and four received serious injuries. Of the surviving passengers, 84 received no injuries, 96 received minor injuries, and 53 received serious injuries. By April 24, 1993 all but three of the surviving passengers were discharged from the hospital.

The National Transportation Safety Board report found that the handle used to actuate the leading edge flaps/slats was poorly designed, and the captain likely moved this handle unintentionally while performing an unrelated task. This unexpected slats deployment caused the nose to pitch up. The pilot returned the handle to the correct position and, in an effort to correct the plane's pitch, pushed the control column forward with enough force to trigger the autopilot to disengage, thus causing an abrupt nose-down elevator movement. The plane continued to oscillate between nose up and nose down pitch due to the pilot's over-correction of the elevator inputs until they were able to stabilize the plane's attitude. The violent pitching movement caused injuries to the occupants. At the time of the accident, passengers were either not wearing seat belts or had them loose, or were standing in the aisle, exacerbating the number and extent of injuries.

Other contributing factors included the lack of pilot training in high altitude upset recovery, the light control force characteristics at cruising altitude, and the influence of the stall warning system engaging and disengaging during the oscillations on the pilot's control inputs.

• The flight will be the subject of an episode in the 25th season of the Canadian documentary series Mayday. The episode is set to be titled "Cabin Chaos".