Christiana Lindsey House is a historic home located at Mercer, Mercer County, Pennsylvania. It was built in 1881, and is a 2+1⁄2-story, brick residence with a 2-story rear ell in the Italianate style. It measures 34 feet wide and 39 feet deep. It sits on a raised ashlar sandstone foundation and has a slate covered truncated hipped roof. It features an elaborately detailed full-width front porch. Also on the property is a contributing summer kitchen, built about 1881.

It was added to the National Register of Historic Places in 1998.