Chrostowo Wielkie [xrɔsˈtɔvɔ ˈvjɛlkʲɛ] is a village in the administrative district of Gmina Czernice Borowe, within Przasnysz County, Masovian Voivodeship, in east-central Poland. It lies approximately 3 kilometres (2 mi) south of Czernice Borowe, 12 km (7 mi) west of Przasnysz, and 90 km (56 mi) north of Warsaw.