Chrząstów Wielki (Polish pronunciation: [ˈxʂɔ̃stuv ˈvjɛlkʲi]) is a village in the administrative district of Gmina Parzęczew, within Zgierz County, Łódź Voivodeship, in central Poland. It lies approximately 4 kilometres (2 mi) north-west of Parzęczew, 21 km (13 mi) north-west of Zgierz, and 29 km (18 mi) north-west of the regional capital Łódź.

The village has an approximate population of 85.