Cieszymowo Wielkie [t͡ɕɛʂɨˈmɔvɔ ˈvjɛlkʲɛ] is a village in the administrative district of Gmina Mikołajki Pomorskie, within Sztum County, Pomeranian Voivodeship, in northern Poland. It lies approximately 9 kilometres (6 mi) east of Mikołajki Pomorskie, 20 km (12 mi) south-east of Sztum, and 73 km (45 mi) south-east of the regional capital Gdańsk.

For the history of the region, see History of Pomerania.