The Clairton–Glassport Bridge, officially the Senator Edward P. Zemprelli Bridge is a girder bridge that carries vehicular traffic across the Monongahela River between Glassport, Pennsylvania and Clairton, Pennsylvania.

It was opened on March 2, 1987, replacing a 1928 arch bridge that stood on the same site. The structure also passes over portions of the U.S. Steel Clairton Works, the largest coke producing facility in the United States.