Clarkston railway station is a suburban side platform railway station in the town of Clarkston, East Renfrewshire, Scotland. The station is managed by ScotRail and is on the East Kilbride branch of the Glasgow South Western Line. It was opened in 1866 by the Busby Railway.

The station was opened by the Busby Railway on 1 January 1866. Services were subsequently extended through to East Kilbride by the Caledonian Railway two years later and eventually to High Blantyre (on the Hamilton and Strathaven Railway), though the section beyond East Kilbride closed back in the 1940s. A further pair of connections to the Lanarkshire and Ayrshire Railway were subsequently constructed around 1903-4 by the latter company, though only the south to west one saw regular traffic and even then for just a few months.

Proposals put forward by British Rail in the early 1980s would have seen the former south to east curve reinstated to allow East Kilbride trains to be re-routed via Muirend, Cathcart and Mount Florida to Glasgow Central. The scheme would have seen the branch electrified but the Clarkston to Busby Junction portion would have been closed, along with Giffnock and Thornliebank stations. The plans were not well received and were eventually dropped.

The station has a half-hourly service in each direction (including Sundays) to Glasgow Central and East Kilbride.

Preceding station	National Rail			Following station
Busby		ScotRail Glasgow South Western Line		Giffnock
	Historical railways
Busby Line and station open		Caledonian Railway Busby Railway		Giffnock Line and station open

• Butt, R. V. J. (October 1995). The Directory of Railway Stations: details every public and private passenger station, halt, platform and stopping place, past and present (1st ed.). Sparkford: Patrick Stephens Ltd. ISBN 978-1-85260-508-7. OCLC 60251199. OL 11956311M.
• Jowett, Alan (March 1989). Jowett's Railway Atlas of Great Britain and Ireland: From Pre-Grouping to the Present Day (1st ed.). Sparkford: Patrick Stephens Ltd. ISBN 978-1-85260-086-0. OCLC 22311137.
• Jowett, Alan (2000). Jowett's Nationalised Railway Atlas (1st ed.). Penryn, Cornwall: Atlantic Transport Publishers. ISBN 978-0-906899-99-1. OCLC 228266687.
• RAILSCOT on Busby Railway

• Historical timetables, maps and satellite imagery for Clarkston railway station. See Timetable World - The online collection of historical transport timetables and maps from around the world