Cobán (Kekchí: Kob'an), fully Santo Domingo de Cobán, is the capital of the department of Alta Verapaz in central Guatemala. It also serves as the administrative center for the surrounding Cobán municipality. It is located 219 km from Guatemala City.

As of the 2018 census, the population of the city of Cobán was 212,047 and that of the municipality was 212,421. Cobán lies at an altitude of 1,320 metres or 4,330 feet above sea level and covers a total area of 1,974 km. It is located at the center of a major coffee-growing area.

The name "Cobán" comes from Q'eqchi' (between clouds)

Between 1530 and 1531, captain Alonso de Ávila [es] on his way to Ciudad Real accidentally discovered the lagoon and hill of Lacam-Tún [es]. People of that place had historically traded with all the people that the Spaniards had conquered, so, knowing what was coming, they sought refuge in the jungle. The Spaniards tried in vain to conquer the lacandones: from Nueva España Juan Enríquez de Guzman tried; from the Yucatán Peninsula, Francisco de Montejo tried; Pedro de Alvarado attempted it from Guatemala along with captain Francisco Gil Zapata and, finally, Pedro Solórzano from Chiapas. That is when the Order of Preachers tried to convert the Tezulutlán "War Zone" into a peaceful region.

In the meantime, after a series of setbacks in La Española, the island Audiencia allowed Bartolomé de las Casas to accept Friar Tomás de Berlanga's invitation to go to Nueva Granada in 1534, where he had just been appointed as Bishop. Both sailed toward Panamá, to then continued to Lima, but during the trip a storm tossed their ship to Nicaragua, where Las Casas chose to remain in the Granada convent. in 1535, he proposed to the King and the Council of the Indies to start a peaceful colonization of the unexplored rural zones in the Guatemala region; however, in spite of Bernal Díaz de Luco and Mercado de Peñaloza intentions to help him, his suggestion was rejected. In 1536 Nicaraguan governor Rodrigo de Contreras organized a military expedition, but Las Casas was able to postpone it by a couple of years after he notified queen Isabel de Portugal, wife of Carlos V. Given the authorities' hostility, Las Casas left Nicaragua and went to Guatemala.

In November 1536, Las Casas settled in Santiago de Guatemala, then the capital of Guatemala; a few months later, his friend, bishop Juan Garcés, invited him to move to Tlascala, but after a few weeks he came back to Guatemala. On May 2, 1537, governor Alonso de Maldonado granted him the Tezulutlán Capitulations - a written commitment ratified on July 6, 1539, by Antonio de Mendoza, México Viceroy- in which everybody agreed that Tezulutlán natives, once conquered, would not be given as encomienda but would be King's subjects. Las Casas, along with friars Rodrigo de Landa, Pedro Angulo and Luis de Cancer, looked for four Christian natives and taught them Christian hymns where the Gospel's basic principles were explained. Luis de Cancer visited the cacique of Sacapulas and was able to perform the first baptisms among his people. Later, Las Casas lead a retinue to bring girts to the cacique, who was so impressed that he decided to convert and become his people preacher. The cacique was baptized with the name of Don Juan and the natives granted permission to build a small church; however, Cobán, another cacique, burned the church. Don Juan, along sixty men, Las Casas and Pedro Angulo, went to talk to Cobán's people and convinced them of their good intentions; Don Juan even took the initiative to marry one of his daughters with cacique Cobán by the Catholic Church.

In 1539 pope Paul III authorized the diocese of Ciudad Real; that year, Alonso de Maldonado—under pressure by Spanish settlers—began a military campaign in Tezulutlán [...] gave all the natives in encomiendas. This flagrant violation of the Capitulations enraged Las Casas, who traveled to Spain to denounce it before king Charles V. On January 9, 1540, a royal document was issues which the Tezulutlán Capitulations [es] were ratified and gave the region to the protection of the Order of Preachers. On October 17 of that year, Cardinal García de Loaysa -then president of the Indias Council- ordered the México Audiencia to comply with these laws. The Capitulations were officially published on January 21, 1541, in the church of Sevilla.

Las Casas was appointed bishop of Chiapas in 1544, but he tried to apply the new ways in his diocese, they were flatly rejected by the encomenderos. In 1545, Guatemala bishop Francisco Marroquín visited Tezulutlán and met with the preachers. Back in the city of Gracias a Dios, where the Audiencia de los Confines had its main office- met with Las Casas and with Nicaragua bishop Antonio de Valdivieso. There was a lot of tension between Marroquín and Las Casas in this meeting The conflict moved on to Ciudad de México and finally everybody agreed to favor the freedom of the natives; however, this could not be accomplished for the Lacandon Jungle would not be conquered for another two century, becoming the rebel maya people favorite hideout.

Las Casas and Angulo founded Rabinal, and the city of Cobán was the center of the new Catholic doctrine. A few years later, the natives started settling following the Spanish model and several towns were settled, like Tactic. The name "War zone" was change for "Vera Paz" (true peace), name that became official in 1547. Cobán received the title of an imperial city by Charles V, Holy Roman Emperor and in 1599 Cobán became bishop's see. It was briefly known during this period as Ciudad Imperial (Spanish for "Imperial City") in Charles's honor.

As of 1850, Cobán population was estimated to be at 12000. Ca. 1890, British archeologist Alfred Percival Maudslay and his wife moved to Guatemala, and visited Cobán. Around the time the Maudslays visited Verapaz, a German colony had settled in the area thanks to generous concessions granted by liberal presidents Manuel Lisandro Barillas Bercián, José María Reyna Barrios and Manuel Estrada Cabrera. The Germans had a very united and solid community and had several activities in the German Club (Deutsche Verein), in Cobán, which they had founded in 1888. Their main commercial activity was coffee plantations. Maudslay described the Germans like this: "There is a larger proportion of foreigners in Coban than in any other town in the Republic: they are almost exclusively Germans engaged in coffee-planting, and some few of them in cattle-ranching and other industries; although complaints of isolation and of housekeeping and labour troubles are not unheard of amongst them, they seemed to me to be fortunate from a business point of view in the high reputation that the Vera Paz coffee holds in the market, and the very considerable commercial importance which their industry and foresight has brought to the district; and, from a personal point of view, in the enjoyment of a delicious climate in which their rosy-cheeked children can be reared in health and strength, and in all the comforts which pertain to a life half European and half tropical. Hotels or fondas appear to be scarce; but the hospitality of the foreign residents is proverbial."