Collison House is a historic home located at Newport, New Castle County, Delaware. It was built about 1885, and is a 2+1⁄2-story, three bay by three bay, square frame dwelling with a mansard roof in the Second Empire style. The mansard roof has broad gable dormers and the house features a two-story, projecting bay. It has a full width, hipped roof porch on the front facade.

It was added to the National Register of Historic Places in 1993.