Comber railway station was on the Belfast and County Down Railway which ran from Belfast to Newcastle, County Down in Northern Ireland.

The station was opened by the Belfast and County Down Railway on 6 May 1850 as the penultimate station on the original single-track line to Newtownards. With the opening of the branch to Ballygowan and Downpatrick in 1958, it became a junction. The Newtownards branch was eventually extended to Donaghadee and the Downpatrick line to Newcastle.

The station closed to passengers in 1950, by which time it had been taken over by the Ulster Transport Authority. The station buildings, with the exception of the goods shed, were demolished and a section of the trackbed running through the station relaid as the A22 bypass.

Preceding station	Historical railways			Following station
Dundonald		Belfast and County Down Railway Belfast-Newcastle		Ballygowan
Dundonald		Belfast & County Down Railway Donaghadee Branch Belfast-Donaghadee		Newtownards

• Butt, R. V. J. (October 1995). The Directory of Railway Stations: details every public and private passenger station, halt, platform and stopping place, past and present (1st ed.). Sparkford: Patrick Stephens Ltd. ISBN 978-1-85260-508-7. OCLC 60251199. OL 11956311M.
• Jowett, Alan (March 1989). Jowett's Railway Atlas of Great Britain and Ireland: From Pre-Grouping to the Present Day (1st ed.). Sparkford: Patrick Stephens Ltd. ISBN 978-1-85260-086-0. OCLC 22311137.
• Jowett, Alan (2000). Jowett's Nationalised Railway Atlas (1st ed.). Penryn, Cornwall: Atlantic Transport Publishers. ISBN 978-0-906899-99-1. OCLC 228266687.

54°33′06″N 5°45′16″W / 54.551576°N 5.754529°W / 54.551576; -5.754529