Cornell Glacier (Greenlandic: Ikissuup Sermersua, old spelling: Ikigssûp Sermerssua, Danish: Cornell Gletscher) is a tidewater glacier in Avannaata municipality on the northwestern shore of Greenland. It drains the Greenland ice sheet westwards into Nuussuup Kangia, a fjord inlet of Sugar Loaf Bay, to the east of the base of Nuussuaq Peninsula.