Cristóbal Island (in Spanish: Isla San Cristóbal, or Saint Christopher's Island) is a mostly deforested 37 km island located south of Isla Colón, in the Bocas del Toro Archipelago, Panama. It is home to the indigenous Ngäbe or Guaymí people and a small number of expatriates. Laguna Bocatorito, also known as Dolphin Bay, lies on the east side of the island.

The island is part of the Bocas del Toro Important Bird Area (IBA), designated as such by BirdLife International because it supports significant populations of white-crowned pigeons and three-wattled bellbirds.

• List of islands of Panama