Cuatro Ciénegas is one of the 38 municipalities of Coahuila, in north-eastern Mexico. The municipal seat lies at Cuatrociénegas de Carranza. The municipality covers an area of 7860.6 km.

As of 2020, the municipality had a total population of 12,715.

Cuatrociénegas is famous for its endemic species and has been awarded the "Pueblo Mágico" (Magic Town) category by the tourism department.