Cypress Inn is an unincorporated community in Wayne County, Tennessee, United States. It is located near the Alabama state line and is along the Natchez Trace Parkway.

Historical records state that the Cypress Inn was the name of an inn along the Natchez Trace. The area grew into a community; even though the inn no longer exists, the name of the community is Cypress Inn. Much of the land has been owned by the same families for generations. Local families include Braunius, Holt, Dodd, Berry, Darby, Montgomery, and Pigg.

• Cypress Inn Volunteer Fire Department

• Collinwood, Tennessee
• Cloverdale, Alabama
• Iron City, Tennessee
• Waterloo, Alabama
• Florence, Alabama

• Lutts, Tennessee

• Tennessee State Route 227
• Natchez Trace Parkway

35°00′43″N 87°49′00″W / 35.01194°N 87.81667°W / 35.01194; -87.81667