Dźwierszno Wielkie [ˈd͡ʑvjɛrʂnɔ ˈvjɛlkʲɛ] is a village in the administrative district of Gmina Łobżenica, within Piła County, Greater Poland Voivodeship, in west-central Poland. It lies approximately 9 kilometres (6 mi) north-east of Łobżenica, 46 km (29 mi) east of Piła, and 105 km (65 mi) north of the regional capital Poznań.