Dalrymple Creek is a locality in the Shire of Hinchinbrook, Queensland, Australia. In the 2021 census, Dalrymple Creek had a population of 51 people.

The Herbert River forms the south-western boundary of the locality and most of the developed land is on the river flats and predominantly used for growing sugarcane. The rest of the locality is mountainous and mostly undeveloped except for a section within the Abergowrie State Forest.

Mount Cadillah is a named peak in the west of the locality (18°28′55″S 146°01′39″E / 18.4819°S 146.0275°E / -18.4819; 146.0275 (Mount Cadillah)).

The locality takes its name from the Dalrymple Creek which flows through the locality, a tributary of the Herbert River. The creek in named was named after George Elphinstone Dalrymple, an explorer, public servant and politician.

In the 2016 census, Dalrymple Creek had a population of 97 people, 48% female and 52% male. The median age of the population was 46 years, 8 years above the national median of 38.

In the 2021 census, Dalrymple Creek had a population of 51 people, 49% female and 51% male. The median age of the population was 54 years, 16 years above the national median of 38.

There are no schools in Dalrymple Creek. The nearest government primary schools are Abergowrie State School in neighbouring Abergowrie to the west and Ingham State School in Ingham to the south. The nearest government secondary school is Ingham State High School, also in Ingham.