DeJulius was born August 9, 1999, in Detroit, Michigan to Latrice Halthon and Ladell DeJulius. He has a brother, Terrell Thornton, and three sisters, Aaliyah DeJulius, Cerisse DeJulius and Latriece DeJulius.
High school
DeJulius attended Edison Public School Academy for his freshman and sophomore seasons. As a freshman, he was selected to the 2015 Class C All-State team (2nd team, The Detroit News; 4th team Detroit Free Press). As a sophomore, he was again selected to the 2016 Class C All-State team (2nd team, The Detroit News; 3rd team Detroit Free Press; honorable mention Associated Press).
DeJulius transferred to East English Village Preparatory Academy for his junior and senior seasons. As a junior, he visited the University of Michigan a few times (including September 17, 2016, and October 25, 2016). He scored 46 points with 7 rebounds and 5 assists against Dakota High School and Michigan State Spartans men's basketball signee Thomas Kithier in front of head coachJohn Beilein and the entire coaching staff on December 17, 2016. DeJulius got an offer and gave a verbal commitment on December 22. At the time, he was the 172nd ranked player in the national class of 2018 and the 32nd ranked point guard. DeJulius was a 2017 Class A All-state honoree (1st team Associated Press).
With 2,542 points, DeJulius finished 3rd behind Michigan State signee Foster Loyer (3,691) and Michigan signee Brandon Johns (2,792) in the 2018 Mr. Basketball of Michigan voting. In his only head-to-head meeting with Loyer, DeJulius scored 42 points in an 80–71 comeback to give Clarkston High School its only regular season loss against 21 points, 12 assists, and eight rebounds from Loyer. East English had trailed in the battle of the state's two best point guards 49–31 at halftime and 63–53 after three quarters. Then, DeJulius had 25 points in the second half, including 17 in the fourth quarter, against the defending 2017 Michigan High School Athletic Association Class A state champions, who would repeat in 2018. DeJulius was a 2018 All-class first team All-state selection by The Detroit News.
On November 15, Michigan defeated Elon 70–50 DeJulius added 10 points and eight assists, which were both career highs at the time. On November 27, Michigan defeated Iowa State 83–76 in the quarterfinals of the Battle 4 Atlantis tournament. DeJulius added a career-high 14 points. On January 28, with Simpson suspended and Isaiah Livers sidelined, DeJulius started against Nebraska and played 34 minutes. On March 8, Michigan lost to (#9/#9) Maryland 70–83 in their final game of the regular season. Michigan was led by DeJulius with a career-high 20 points. Michigan was scheduled to play Rutgers in the Big Ten tournament on March 12. However, the tournament and the remainder of the college basketball season was cancelled due to the coronavirus pandemic.
DeJulius entered the NCAA transfer portal in April 2020 even though Simpson had completed his eligibility and Brooks would be a senior. In the portal, he received interest from Maryland, Missouri, Marquette, Cincinnati, Iowa State, DePaul, Rhode Island, Creighton and Arizona State. With over 20 schools expressing interest, DeJulius announced four finalists by April 10: Iowa State, Cincinnati, Marquette and Missouri. During his sophomore year with the Wolverines, DeJulius scored 10 or more points in eleven games. There was speculation that he might secure the starting point guard position if he continued with the team. However, Michigan had been pursuing point guards Bryce Aiken and Mike Smith in the transfer portal and recruiting Josh Christopher prior to DeJulius's announcement that he would transfer.
On January 30, 2022, he scored the go-ahead basket with 3.7 seconds left against East Carolina. DeJulius posted 3 consecutive 20-point games on February 6 (25, #6 Houston), February 9 (24, South Florida), and February 12 (23, Tulsa), marking the first such streak by a Bearcat since Jarron Cumberland did so for the 2018–19 Bearcats over 3 years before. On February 24, 2022, he announced that he would not partake in Senior Night fanfare, in part because he was eligible to return with another year due to special COVID-19 waiver. DeJulius earned third-team All-American Athletic Conference as a true senior for the 2021–22 Cincinnati Bearcats men's basketball team. He averaged a team-leading 14.5 points per game, was the team's only All-AAC performer and decided to exercise his option to return.
COVID Redshirt 5th year season
DeJulius earned 2022–23 Preseason All-Conference Second Team recognition for his redshirt senior season. Before the season, he announced that he would donate his student athlete compensation proceeds from his team-licensed jersey sales to provide books to inner city youth in Detroit and Cincinnati. He began the season by leading the 2022–23 Cincinnati Bearcats to three victories, averaging 21.3 points and 3.7 assists while shooting 56.1% from the field, including 7-of-9 on three-point shots, and earning American Athletic Conference player of the week honors. When DeJulius was honored on March 5, 2023 Senior Night, along with Kalu Ezikpe and Rob Phinisee prior to the game against SMU, he posted a career-high 30 points with 6 assists. He repeated as an All-American Athletic Conference third-team honoree. DeJulius entered the 2023 American Athletic Conference men's basketball tournament with the nation's longest streak of five or more assists (16 games). In the 2023 National Invitation Tournament first round victory over Virginia Tech, DeJulius had 21 points, 6 rebounds and 7 assists. After three years at Cincinnati, DeJulius posted 1187 points and ended his final season with 192 assists, which is third in school history behind two Oscar Robertson totals on the school list for single-season assists.
Professional career
On August 3, 2023, DeJulius signed his first professional contract overseas with Greek club Lavrio. He averaged 14.4 points, 2.9 rebounds and 2.2 assists per game in the Greek Basket League.
On January 13, 2024, his contract was bought out by German club BG Göttingen, where he averaged 13.6 points and 5.1 assists per game.
On June 22, 2024, DeJulius returned to Greece, signing with Aris Thessaloniki.
On November 4, 2024, DeJulius moved to EuroLeague mainstays Maccabi Tel Aviv, signing a two-year contract. Aris received a 200.000€ buyout for the completion of the transfer.