DeSoto Falls is a 104-foot (32 m) waterfall located on the West Fork of the Little River near Mentone, Alabama, United States, in DeSoto State Park. The falls have carved their own small canyon. They are named after Spanish explorer Hernando de Soto.

• DeSoto State Park, Alabama
• DeSoto and Other Alabama Waterfalls

34°33′N 85°35′W / 34.55°N 85.59°W / 34.55; -85.59