Dededo (Chamorro: Dedidu; formerly in Spanish: [deðeðo]) is the most populated village in the United States territory of Guam. According to the U.S. Census Bureau, Dededo's population was just under 45,000 in 2020. The village is located on the coral plateau of Northern Guam. The greater Dededo-Machanao-Apotgan Urban Cluster had a population of 139,825 as of the 2010 census, making up 87.7% of Guam's population and 29.8% of its area.

The origin of the village name Dededo, Dedidu in Chamorro, may come from the practice of measuring using fingers. The Spanish word for finger is dedo. It can be theorized that someone measured out the original village this way. Another possibility is that the word "dededo" is a version of the word "dedeggo," which means "heel of the foot," or that it comes from the word "deggo" which means to "walk on tiptoes."

Before World War II, Dededo Village was at the bottom of Macheche Hill. Dededo grew into a major village after the war when the U.S. Navy constructed housing for displaced Guamanians and for laborers coming from off-island to help in Guam's development.

Following Typhoon Karen in 1962, Kaiser Subdivision in Dededo was constructed for islanders displaced by the storm. Further housing subdivisions were constructed increasing the village's population.

The first McDonalds in Guam was opened here on 10th June, 1971.

In 1984, the Northern Community Health Center opened. In addition to traditional health services provided by the village clinics, this center offered communicable disease control services and dental health as well as chronic disease care and crippled children services.

In October 1988, the island's first large-scale and fully enclosed shopping mall, the Micronesia Mall, opened.

U.S. military installations in the village include Marine Corps Base Camp Blaz, Naval Computer and Telecommunications Station Guam, and portions of Andersen Air Force Base, including Northwest Field.

The U.S. Census Bureau has the municipality in multiple census-designated places: Dededo, Astumbo, Finegayan Station, Liguan, Machanao, Machananao East, Machananao West, Macheche, Mogfog, Ukudu, Wusstig, Y Papao, and Y Sengsong.

Micronesia Mall is the largest shopping mall in Guam and serves as a cultural and recreational venue as well, with movie theaters and an amusement park.

There is also a popular weekend flea market in town which attracts large crowds of vendors.

Dededo is situated on a relatively flat limestone plateau in the northern part of the island. It is located at the north central part of the island roughly at the center of population. It encompasses an area of about 30 square miles (78 km) of Guam's 209 square miles (540 km). The headquarters for the Guam National Wildlife Refuge are in Dededo.

Tourist sites in Dededo include the Ritidian Unit of the Guam National Wildlife Refuge, the Micronesia Mall, Two Lovers Point, as well as parks, trails, and beaches. Beaches include Tanguisson Beach, Shark Cove Beach, Haputo Beach, and Urono Beach. Haputo and Urono Beaches are listed on the U.S. National Register of Historic Places. The South Finegayan Latte Stone Park is also listed on the National Register of Historic Places.

The Federal government of the United States owns portions of the land in Dededo; the Government of Guam stated that it was one of several villages that are "characterized primarily by the large proportion of land owned by the federal government".

Dededo has several public and private schools to accommodate the growing number of residents of the island's most populous village including Guam Department of Education institutions. The village is served by six elementary schools, two middle schools, and one high school.

In regards to the Department of Defense Education Activity (DoDEA), Dededo is in the school transportation zone for Andersen Elementary and Andersen Middle School, while Guam High School is the island's sole DoDEA high school.

Private schools:

• Santa Barbara Catholic School
• St. Paul's Christian School
• Pacific Christian Academy

Commissioner of Dededo
Name	Term begin	Term end
Jose F. Lujan	1932	1934
Ignacio A. Santos	1934	1940
Juan Pangelinan	1940	1941
Hector Sgambelluri	1941	1944
Ramon S. San Agustin	1944	1952
Vicente S.A. Benavente	1952	1976
Prospero C. Zamora	1976	January 3, 1977

Mayor of Dededo
Name	Party	Term begin	Term end
Jose M. Garrido	Republican	January 3, 1977	January 5, 1981
Martin C. Benavente	Democratic	January 5, 1981	January 7, 1985
Patricia S. Quinata		January 7, 1985	January 2, 1989
Jose A. Rivera	Republican	January 2, 1989	January 1, 2001
Scott D. Duenas		January 1, 2001	January 3, 2005
Melissa B. Savares	Democratic	January 3, 2005	present

Assistant Commissioner of Dededo
Name	Term begin	Term end
Ignacio A. Santos	1918	1934
Manuel M. Lujan	1934	1941
Teresita B. Umagat	1971	1973
Prospero C. Zamora	1973	January 3, 1977

Vice Mayor of Dededo
Name	Party	Term begin	Term end
Erwin F. Flauta	Democratic	January 3, 1977	1978
Martin C. Benavente		1978	January 5, 1981
Patricia S. Quinata		January 5, 1981	January 7, 1985
Jose A. Rivera	Republican	January 7, 1985	January 2, 1989
Doris S. Palacios		January 2, 1989	January 1, 2001
Melissa B. Savares	Democratic	January 1, 2001	January 3, 2005
Andrew A. Benavente		January 3, 2005	January 2, 2017
Frank A. Benavente	Republican	January 2, 2017	January 4, 2021
Peter J.S. Benavente	Democratic	January 4, 2021	present

Wettengel Rugby Field and GFA National Training Center are located in Dededo. Guam Track and Field Association is also located in the village.

• Joe Duarte, mixed martial artist
• Ping Duenas, politician
• Louise Borja Muna - Guamanian singer, radio host, and politician.
• Anthony Paulino, soccer player
• Regine Tugade, sprinter

• 
  Santa Barbara School
• 
  Maria A. Ulloa Elementary School in Dededo

• Rogers, R. F. (1995). Destiny's Landfall: A History of Guam. University of Hawai'i Press. ISBN 0-8248-1678-1.

• Dededo Village – Guampedia