Denkyira District is a former district council that was located in Central Region, Ghana. Originally created as a district council in 1975, it was split off into two new district assemblies in 1988: Upper Denkyira District (capital: Dunkwa-On-Offin) and Twifo/Heman/Lower Denkyira District (capital: Twifo Praso). The district council was located in the northwest part of Central Region and had Dunkwa-On-Offin as its capital town.

5°58′0.12″N 1°46′59.88″W / 5.9667000°N 1.7833000°W / 5.9667000; -1.7833000