Depułtycze Królewskie [dɛpuu̯ˈtɨt͡ʂɛ kruˈlɛfskʲɛ] is a village in the administrative district of Gmina Chełm, within Chełm County, Lublin Voivodeship, in eastern Poland. It lies approximately 2 kilometres (1 mi) south of Pokrówka, 8 km (5 mi) south of Chełm, and 65 km (40 mi) east of the regional capital Lublin.

During the January Uprising, on August 5, 1863, it was the site of the Battle of Depułtycze, in which Polish insurgents defeated Russian troops.