Detroit Lakes station is an Amtrak intercity train station in Detroit Lakes, Minnesota, served by Amtrak's daily Empire Builder. The building was originally built by the Northern Pacific Railroad and has been listed on the National Register of Historic Places since 1988 as the Northern Pacific Passenger Depot.

The station was renovated in 2010 under the direction of the local White Earth Reservation and the Minnesota Department of Transportation. The exterior brickwork was cleaned; wood soffits repaired; and window and door trim painted. On the interior, the space was reconfigured to accommodate retail kiosks.

The station is one of three in Minnesota and 78 across the Amtrak network listed in a 2021 settlement with the U.S. Department of Justice over inaccessible facilities under the Americans with Disabilities Act. Under the company's ADA Stations Program (ADASP), new station platforms, walkways, lighting, and other accessibility improvements will be constructed between Amtrak's fiscal year 2025 and 2027.

In 2023, $4 million was included in the Minnesota state budget to study a daytime train service between the Twin Cities and Fargo, North Dakota, a service that would include stops at Detroit Lakes station.

Media related to Detroit Lakes (Amtrak station) at Wikimedia Commons

• Detroit Lakes, MN – Amtrak
• Detroit Lakes, MN – Station history at Great American Stations (Amtrak)
• Detroit Lakes Amtrak Station (USA Rail Guide -- Train Web)