Didessa National Park is a national park in western Ethiopia. It is located in the valley of the Didessa River, in Kamashi Zone of Benishangul-Gumuz Region in western Ethiopia. It covers an area of 1300 km.

It was designated a national park in 2017 by the Government of Ethiopia. It had previously been designated a wildlife sanctuary. It is known for its lush forests, towering waterfalls, and escarpments. This is home to a wide range of wildlife, including baboons, warthogs, bush-bucks, and Ethiopian wolf.